Jurgen Klopp will have to contend with a number of injuries if his Liverpool side are to claim all three points from Southampton
Xavi goes into his third match as Barcelona head coach undefeated but facing a major challenge against Villarreal in La Liga
Thomas Muller is now the outright leader in the standings, but Mo Salah and Kylian Mbappe have closed the gap and are level with Paul Pogba and Karim Benzema.
Real Madrid boss Carlo Ancelotti may stick with a winning formula as Los Blancos travel to Tiraspol
Liverpool manager Jurgen Klopp has a few selection problems ahead of the Champions League tie versus Porto
One of the biggest fixtures in Matchday Four in the Champions League sees Pep Guardiola reunited with Lionel Messi
Carlo Ancelotti’s side won easily at Granada to take advantage of Real Sociedad’s draw and move clear at the summit
Robert Lewandowski has scored the most goals from Europe’s top five leagues so far this campaign
Liverpool forward Mohamed Salah is leading the race for Golden Boot glory on 10 goals
Chelsea and Juventus could welcome back injured players ahead of their Champions League tussle.